Two sample MR report
PARK7_Monocyte (Mono) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | -0.0511332 | 1.2713057 | 0.9698444 |
| Weighted median | 6 | -0.0580827 | 0.0254951 | 0.0227154 |
| Inverse variance weighted | 6 | -0.0551825 | 0.0218707 | 0.0116315 |
| Simple mode | 6 | -0.0594433 | 0.0352213 | 0.1522709 |
| Weighted mode | 6 | -0.0590973 | 0.0361353 | 0.1628829 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.3786185 | 4 | 0.9841897 |
| Inverse variance weighted | 0.3786286 | 5 | 0.9958978 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0012438 | 0.3904403 | 0.9976108 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.9e-05 | 0 | TRUE | 0.465772 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
